AVANSCURE LIFESCIENCES PVT. LTD.
Asenapine maleate 

Asenapine maleate 

Send Inquiry
Asenapine maleate

≥98% (HPLC)

Synonym: (3aRS,12bRS)-5-Chloro-2-methyl-2,3,3a,12btetrahydro-1Hdibenzo[2,3:6,7]oxepino[4,5-c]pyrrole (2Z)-2-butenedioate, Org 5222, trans-5-Chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-dibenz(2,3:6,7)oxepino(4,5-c)pyrrole maleate
  • CAS Number :85650-56-2
  • Empirical Formula (Hill Notation) C17H16ClNO ·C4H4O4
  • Molecular Weight 401.84  
  • assay      ≥98% (HPLC)
  • form      powder
  • color      white to off-white
  • solubility      H2O: ≥10 mg/mL   
  • storage temp.      2-8°C
Biochem/physiol Actions

Asenapine maleate is a 5-HT receptor antagonist (5-HT1A,1B, 5-HT2A, 2B, 2C, 5-HT5A, 5-HT6 and 5-HT7), a D2 antagonist, and an antipsychotic.

Application

Asenapine maleate is a serotonin 5-HT and dopamine D2 receptor antagonist. Asenapine maleate can be used to treat schizophrenia and bipolar mania.